GeoMx Space Biology Technology Lecture

Introduction to GeoMx Spatial Biology Technology: GeoMx Digital Spatial Profiler is a novel platform developed by NanoString. Digital Spatial Profiling is based on the nCounter barcoding technology that enables spatially resolved, digital characterization of proteins or mRNA in a highly multiplexed (up to 18,000-plex ) assay. The assay relies upon antibody or RNA probes coupled to photocleavable oligonucleotide tags. After hybridization of probes to slide-mounted formalin fixed paraffin-embedded (FFPE) tissue sections, the oligonucleotide tags are released from discrete regions of the tissue via UV exposure.Released tags are quantitated in a standard nCounter assay, and counts are mapped back to tissue location, yielding a spatially- resolved digital profile of analyte abundance.

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Email:genomics@cibr.ac.cn
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Address：Beijing brain science and brain like research center, No.26 Science Park, Zhongguancun Life Science Park, Changping District, Beijing
Web:http://www.cibr.ac.cn